Science-Backed Anti-Aging Technology
upLift 5 harnesses u5 Nano-Pulse Technology, a high-frequency, low-magnitude vibration (HFLMV) method that stimulates fibroblast and osteoblast production.
As you gently bite down, the device’s non-invasive pulsations activate your body’s natural renewal process. This stimulates the creation of osteoblasts, essential for building cheekbones, jawline, eye sockets, and brow bones. Simultaneously, fibroblasts are produced, which are key to collagen and elastin generation for healthier, more youthful skin and muscle.
Increases Anti-Aging Growth Factors


Alikhani M, Khoo E, Alyami B, Raptis M, Salgueiro JM et al. Osteogenic Effect of High frequency Acceleration on Alveolar Bone. J Dent Res. 2012;91(4):413-9.
In outer space, astronauts lose bone mass much faster than here on Earth due to the lack of gravitational forces. As we age on earth, our bone degenerates faster than new bone is created. upLift 5 employs u5 Nano-Pulse, based on high-frequency, low-magnitude vibration technology originally developed by NASA researchers for long-term missions in space. u5 Nano-Pulse targets facial structure, muscle, and all layers of skin from the inside out.
Patent-Pending to Treat Skin Laxity
upLift 5 is programmed to create u5 Nano-Pulses, gentle pulses that refresh and revitalize your face and neck in just 5 minutes a day. The pulses travel through the facial bone and muscle to treat the aging appearance resulting from skin laxity. Skin laxity is a major contributor to the appearance of fine lines & wrinkles, sagging, jowls, deep forehead lines, crow’s feet, lip lines and smile lines. Regular use can help lift and firm your skin, giving you a smoother, more youthful appearance.


Increases Osteoblast Proliferation to Build New Bone
u5 Nano-Pulses are specifically in the range necessary to create osteoblasts, the building blocks of new bone. Daily use of the upLift 5 can help maintain a youthful appearance by increasing bone volume and density in the entire facial structure, including the jawline, cheekbones, eye sockets, temples, brow line, and forehead.

Improves Bone Quantity and Quality
28
DAYSBone Volume
19%Trabecular
27%Trabecular Space
-26%KEY FINDINGS
- HFV produced statistically significant increase in fibroblast proliferation
STUDY DESIGN
- Prospective In Vitro Culture Test
- New York University laboratory
METHODS
- Human Osteoblasts and Fibroblasts divided into 2 study groups
Alikhani M, Khoo E, Alyami B, Raptis M, Salgueiro JM et al. Osteogenic Effect of High frequency Acceleration on Alveolar Bone. J Dent Res. 2012;91(4):413-9.


Increases Fibroblast Proliferation to Create New Collagen and Elastin
u5 Nano-Pulse is specifically in the range necessary to increase production of fibroblasts, the building blocks of new collagen and elastin. Collagen and elastin work together in your skin and muscle. Collagen gives soft tissue strength and resilience, and elastin allows the soft tissue to be flexible while enabling it to return to its original shape. Daily use of the upLift 5 can help maintain a youthful appearance by keeping facial muscle resilient and flexible and maintaining skin laxity, a major contributor to the appearance of fine lines & wrinkles, sagging, jowls, deep forehead lines, crow’s feet, lip lines and smile lines.

KEY FINDINGS
- HFV produced statistically significant increase in fibroblast proliferation
STUDY DESIGN
- Human Osteoblasts and Fibroblasts
RESULTS
- Increased number of fibroblasts
Differential Efficacy of two Vibrating Orthodontic Devices to Alter the Cellular Response in Osteoblasts, Fibroblasts and Osteoclasts | Dose Response
Doctor-Approved
upLift 5 has been developed by doctors to be better than serums, creams, toners, and other beauty products that only affect the top layer of skin with temporary results. upLift 5 activates the body’s natural regeneration process from the inside out – for lasting results. The non-invasive u5 Nano-Pulse technology has been specifically designed to work with and complement some invasive skincare treatments like Botox or fillers, not break them down like other devices may.
